ea0090p190 | Reproductive and Developmental Endocrinology | ECE2023
Guerra-Carvalho Barbara
, Matos Beatriz C.
, Carrageta David F.
, Bernardino Raquel L.
, Oliveira Pedro F.
, Alves Marco G.
Introduction: Mitochondrial uncoupling proteins (UCPs) are transmembrane channels present in the inner mitochondrial membrane whose function is the transport of protons and small substrates between the intermembrane space and the mitochondrial matrix. UCPs are key regulators of cellular metabolism, including mitochondrial function, oxidative phosphorylation, and reactive oxygen species (ROS) production. UCPs dysfunction has been associated with the onset of metabolic dis...